USC’s introduction to the Big Ten has been rough, as Saturday’s 24-17 last-minute loss at Minnesota showed. Penn State, ranked fourth in the country, will look to leave Los Angeles undefeated. The Boilermakers are a trainwreck and remain winless against FBS competition. They visit No. 23 Illinois, which is coming off a bye.

The USC Trojans host the No. 4 ranked Penn State Nittany Lions at 12:30 pm PST on CBS. What did ESPN’s College Gameday crew have to say about the matchup on Saturday morning’s show?

Can Penn State cover against the Trojans at the Coliseum? Will Iowa bounce back at home against UW? Geoff Schwartz breaks down his bets for college football Week 7.

Newsweek's guide to how to bet Penn State vs. USC breaks down the No. 4 Nittany Lions' trip to L.A. for its first game of the season against a ranked opponent.

We're live from the Coliseum, and we're excited to share our college football odds series by making a Penn State-USC prediction and pick.

SportsLine's model revealed its CFB picks and predictions for USC Trojans vs. Penn State Nittany Lions on CBS and Paramount+

In the Trojan’s first year in the Big Ten, they have an opportunity to make a statement against the Nittany Lions.

Penn State hasn’t throttled opponents (other than hapless Kent State) so far, but it has also yielded just 18 points total in its past three games. It was in one-possession game

Penn State looks to remain unbeaten against a struggling USC Trojans squad. Get the latest insight, odds, and predictions ahead of Saturday's kickoff!

The Penn State Nittany Lions can’t look past this USC Trojans team as they eye an easier back half of their schedule. While PSU can likely make the playoffs with a loss this year, it’s less likely they can make it with a loss to this USC team and our Penn State vs.